Table 3. Relationship between plasma FGF-23 concentrations and change in left ventricular ejection fraction during follow-up in chronic dialysis patients.
| Model | FGF-23 tertiles (RU/ml) difference (95% CI) | Log10 FGF-23 difference (95% CI) |
||
|---|---|---|---|---|
| ≤ 1,966 | 1,967 – 11,492 | > 11,492 | ||
| Unadjusted | 0.0 (REF) | –1.0 (–7.2 to 5.2) | –6.7 (–13.1 to –0.33) | –4.3 (–9.3 to 0.66) |
| Model 1 | 0.0 (REF) | 0.13 (–6.6 to 6.9) | –8.0 (–15.5 to –0.53) | –6.5 (–11.3 to –1.73) |
| Model 2 | 0.0 (REF) | 0.12 (–6.8 to 7.0) | –8.4 (–16.2 to –0.62) | –7.2 (–12.3 to –2.1) |
Model 1: adjusted for age, gender, race, diabetes, hypertension, history of cardiovascular disease, body mass index, systolic blood pressure, serum albumin, hemoglobin, phosphorus, plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D. Model 2: adjusted for covariates in Model 1 plus use of angiotensin converting enzyme inhibitors, angiotensin receptor blockers and β-blockers.