Table 2.
Outcomes | Illustrative comparative benefit* (95% CI) | Relative effect‡ (95% CI) | No of participants (studies) | Quality of evidence§ | ||
---|---|---|---|---|---|---|
Assumed benefit: unscreened per 1000 | Corresponding benefit: screened per 1000 | Absolute benefit per 1000† | ||||
Identification | 32 | 74 (44 to 124) | 42 (12 to 92) | 2.33 (1.39 to 3.89) | 3564 (6) | Moderate |
Referral | 7 | 19 (7 to 50) | 12 (0 to 43) | 2.67 (0.99 to 7.20) | 1400 (3) | Low |
*Assumed benefit was from sum of identified or referred but unscreened women and calculated for rate per 1000. Corresponding benefit and confidence intervals calculated by multiplying assumed benefit by risk ratio (RR) and CIs of unscreened to screened women.
†Absolute benefit calculated with formula 1000 × ACR × (1−RR) where ACR is assumed control risk and based on number per 1000.17
‡Risk ratio.
§GRADE Working Group grades of evidence.18