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. 2014 May 1;28(9):971–982. doi: 10.1101/gad.237149.113

Figure 6.

Figure 6.

Lin28 acts thorough the Let7 pathway to prevent normal kidney development. (A) qRT–PCR analysis of mature Let7 levels in LIN28B, LIN28B;i7s, and control kidneys. Dox was provided from E14.5 until the end of the experiment. (B) Morphology of LIN28B, LIN28B;i7s, and control kidneys. (C) qRT–PCR analysis of the CM markers Six2 and Eya1 in LIN28B, LIN28B;i7s, and control kidneys. (D) H&E staining of LIN28B, LIN28B;i7s, and control kidneys. Note that the Lin28B;i7s kidneys have a normal histology. Bar, 100 μm.