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. 2014 May 6;8:57. doi: 10.3389/fnins.2014.00057

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Copyright © 2014 Thompson, Xhaard, Sakurai, Rainero and Kukkonen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Known amino acid sequence-changing variants of human OX₁ receptor. The variants are OX₁¹⁶⁷ Gly/Ser, OX₁²⁶⁵ Leu/Met, OX₁²⁷⁹ Arg/Glu, OX₁²⁸⁰ Gly/Ala, OX₁²⁸¹ Arg/His, OX₁⁴⁰⁸ Ile/Val, OX₂¹⁰ Pro/Ser, OX₂¹¹ Pro/Thr, OX₂¹⁹³ Cys/Ser, OX₂²⁹³ Ile/Val, OX₂³⁰⁸ Val/Ile, and OX₂⁴⁰¹ Thr/Ile. The findings originate from Peyron et al. (2000) and Olafsdottir et al. (2001). The figure is modified from Kukkonen, J. P. (2013). Physiology of the orexinergic/hypocretinergic system: a revisit in 2012. Am. J. Physiol. Cell. Physiol. 301, C2–C32, © 2013. The American Physiological Society (Kukkonen, 2013).