Table 3.

Relationship between RBC iron and P. falciparum.

Study	Major findings
RBC HEMOGLOBIN
Rudzinska et al., 1965	- P. falciparum metabolizes host RBC hemoglobin - P. falciparum inserts host heme into hemozoin
Okada, 2009	- P. falciparum has a heme oxygenase homolog
Sigala et al., 2012	- P. falciparum lacks both heme oxygenase activity and a canonical heme oxygenase pathway
Loria et al., 1999	- Hydrogen peroxide degrades host heme under conditions that are analogous to the microenvironment of the parasite food vacuole
RBC FERRITIN—UNKNOWN
RBC BIOAVAILABLE IRON—UNKNOWN