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. 2014 May 6;8:155. doi: 10.3389/fnbeh.2014.00155

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Copyright © 2014 Ilango, Kesner, Broker, Wang and Ikemoto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Confirmation of phasic excitation of DA neurons by photo-pulse trains in freely-behaving mice. (A) The perievent spike rasters (top) and histograms (bottom) show photo stimulation-evoked firing of a neuron. Experimenter administered 40 photo trains (PI: 0.2 mW; PF: 20 Hz; PN: 8) of the 0.5 (left) and 0.1 (right) ms pulse-durations with the inter-train intervals varying between 10 and 15 s. Bin = 5 ms. (B). The perievent spike rasters (top) and histograms (bottom) show photo stimulation-evoked firing of a neuron. Experimenter administered 20 photo trains (PD: 1 ms; PI: 0.2 mW; PN: 8) of the 20- (left), 50- (middle), and 100-Hz (right) frequencies with the inter-train intervals varying between 10 and 15 s. Bin = 5 ms. (B') It shows an enlarged histogram for the 100-Hz train. Bin = 2 ms.