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. Author manuscript; available in PMC: 2014 Oct 22.
Published in final edited form as: Nat Commun. 2014 Apr 22;5:3603. doi: 10.1038/ncomms4603

Figure 4. Extensive postnatal AS transitions occur primarily without changes in gene expression.

Figure 4

a. RNA-seq data (UCSC browser) and RT-PCR assays (n=2 biological replicates) for AS events developmentally regulated (+ex: exon included; −ex: exon skipped). See Supplementary Fig. 3, and Supplementary Table 3. b. Correlation between RNA-seq and RT-PCR ΔPSI values. c. Genes undergoing postnatal AS transitions (|ΔPSI|≥20%) were intersected with differentially expressed (DE) genes in ventricles (E17-adult). d. AS transitions (|ΔPSI|≥20%; E17-adult) were plotted comparing their change between E17-PN28 (red) and PN28-adult (green). Diagonal line: no difference between time points. Dots above/below the diagonal: increased/decreased inclusion. AS: alternative splicing. bp: base pairs. PSI: percent spliced in.