Table 1.
Baseline characteristics of total cohort
| Variable | Patients with Diabetes Mellitus | p-value | |
|---|---|---|---|
| Continue group (n=86) | Hold group (n=86) | ||
| Age (years) | 64 [60–74] | 66 [62–73] | 0.25 |
| Men | 85 (99%) | 86 (100%) | 1.0 |
| White | 62 (72%) | 63 (73%) | 0.58 |
| Black | 17 (20%) | 13 (15%) | |
| Hispanic | 7 (8%) | 10 (12%) | |
| Body mass index (kg/m2) | 32 [29–36] | 30 [27–35] | 0.08 |
| Abdominal circumference (inch) | 46 [42–50] | 44 [40–48] | 0.03 |
| Previous myocardial infarction | 23 (27%) | 26 (30%) | 0.74 |
| Hypertension* | 81 (94%) | 81 (94%) | 1.0 |
| Hyperlipidemia* | 77 (90%) | 78 (91%) | 1.0 |
| Chronic kidney disease | 19 (22%) | 13 (15%) | 0.33 |
| Previous stroke | 15 (17%) | 13 (15%) | 0.84 |
| Peripheral vascular disease | 10 (12%) | 17 (20%) | 0.21 |
| Tobacco use | 27 (32%) | 17 (20%) | 0.11 |
| Presenting with acute coronary syndrome | 18 (21%) | 25 (29%) | 0.29 |
| Sulfonylurea | 37 (43%) | 39 (45%) | 0.88 |
| Metformin | 52 (61%) | 53 (62%) | 1.0 |
| Thiazoladinediones | 6 (7%) | 4 (5%) | 0.75 |
| Sitagliptin | 3 (4%) | 0 | 0.25 |
| Long-acting insulin | 39 (45%) | 35 (41%) | 0.64 |
| Multiple glucose-lowering agents | 40 (47%) | 35 (41%) | 0.54 |
| Oral agents only With insulin |
15 (38%) 25 (63%) |
17 (49%) 18 (51%) |
0.36 |
| Ejection fraction | 0.64 | ||
| Normal | 64 (76%) | 63 (74%) | |
| Severely reduced | 6 (7%) | 4 (5%) | |
| Random glucose (mg/dL) | 141 [108–197] | 146 [120–186] | 0.55 |
| Hemoglobin A1c (%) | 7.1 [6.5–8.5] | 7.3 [6.8–8.0] | 0.94 |
| Glomerular filtration rate (mL/min) | 70 [54–84] | 72 [59–98] | 0.08 |
| Low density lipoprotein-cholesterol (mg/dL) | 74 [59–92] | 74 [61–94] | 0.66 |
| High density lipoprotein-cholesterol (mg/dL) | 39 [33–45] | 37 [32–45] | 0.96 |
| Triglyceride (mg/dL) | 151 [106–211] | 145 [105–214] | 0.81 |
| Fasting time (hours) | 16.1 [14.0–19.2] | 17.3 [14.4–19.3] | 0.41 |
*
Hypertension and hyperlipidemia are defined as self-reported history of or documentation of these diagnoses in a physician note in the electronic medical record system.