Table 2. Postoperative Analgesic Requirements for Hypospadias Repair, With and Without Additives.

	LB a, (n = 8)	LB and K a, (n = 52)	LB and C a, (n = 15)	LB, K, and C a, (n = 12)
Time to first analgesia request, min, Median (range)	248 (150-365)	210 (75-900)	295 (65-4365)	253 (80-875)
Acetaminophen requirement in 24 hours, mg/kg, Median (range)	40.4 (22.5-85.6)	31.6 (14.1-81.8)	36.8 (13-67.4)	41.9 (19.1-56.1)
Ibuprofen requirement in 24 hours, mg/kg, Median (range)	4.3 (1.2-12.8)	8.4 (2-22.4)	11.4 (5.1-16)	9.2 (3-11.4)
Time to hospital discharge, min, Median (range)	1410 (220-1570)	1258 (235-7620)	1223 (400-4295)	1223 (265-11855)

^a Abbreviations:C, clonidine; K, ketamine; LB, levobupivacaine