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Amino acid alignment of published Streptomyces (Strep.) two-domain LMCOs and some reference three-domain LMCOs between the conserved copper binding regions (including those of bacteria [Bact.], actinomycetes [Actino.], basidiomycetes [Basid.], and ascomycetes [Asco.]). Similarity shading was applied, with a 100% threshold indicated in black. Degenerate primers for this study were designed based on conserved copper binding regions two (II) and four (IV).
