FIG 5.

Weight loss and survival rates in mice challenged with H5N1 homologous and heterologous viruses. Groups of 18 mice were inoculated i.n. with two doses of 300 MID₅₀s of each virus 28 days apart or mock vaccinated. Four weeks after the second vaccination, mice were challenged with 100 LD₅₀ of HPAI virus VN1203 (A) or EG321 (B). Five mice per group were monitored daily for clinical signs (body weight) and survival rate for up to 14 days after challenge.