TABLE 2.

Number of unique peptides in milk of 3 mothers and in the gastric samples from their infants 2 h after ingestion of their mother’s milk that encompass or partially encompass known functional peptides

No. in milk	No. in gastric sample	Found peptide protein of origin	Position in human protein	Sequence in human protein	Position in matched sequence	Known functional peptide	Activity	Protein	Reference
10	48	β-Casein	120–132	S1PTIPFFDPQIPK	120–132	Q1PTIPFFDPQIPK	Immunomodulation	Human β-casein	(21)
0	8	β-Casein	66–73	YPFVEPIP	66–73	YPFVEPIP	Opioid agonist	Human β-casein	(22)
20	30	β-Casein	200–226	QELLLNPTHQIYPVTQPLAPVHNPISV	200–226	QELLLNPTHQYPVTQPLAPVHNPISV	Antibacterial	Human β-casein	(23)
3	4	β-Casein	53–57	DKIYP	47–51	DKIHP	Antihypertensive	Ovine β-casein	(5)
22	25	β-Casein	101–106	VPKA2KD3	95–100	VPKV2KE3	Antihypertensive	Ovine β-casein	(5)
22	25	β-Casein	101–107	VPKA2KD3T	95–101	VPKV2KE3T	Antihypertensive	Ovine β-casein	(5)
9	30	β-Casein	175–181	KVLPI4PQ	184–190	KVLPV4PQ	Antihypertensive	Bovine β-casein	(24)
12	31	β-Casein	183–189	V2VPYPQR	192–198	A2VPYPQR (β-casokinin-7)	Antihypertensive	Bovine β-casein	(25)
0	4	κ-Casein	55–58	YPYY	79–82	YPYY (casoxin-B)	Opioid antagonist	Bovine κ-casein	(26)

¹Serine > glutamine amino acid polymorphism.

²Alanine/valine replacement.

³Aspartic acid/glutamic acid replacement.

⁴Isoleucine/valine replacement.