FIGURE 1.

Quercetin bioavailability in plasma in C57BL/6 mice and percentage change in body weight, fat, and muscle mass in C57BL/6 and Apc^Min/+ mice supplemented with vehicle or quercetin via oral gavage. Plasma quercetin concentrations (n = 3/time point) (A). Percentage change in body weight pre- and post-intervention (B), epididymal fat (C), and muscle mass (D) at 18 wk of age. Values are means ± SEMs, n = 4–8/group. Means without a common letter differ, P < 0.05. Apc, adenomatous polyposis coli; Apc^Min/+Q, Apc^Min/+ mice gavaged with quercetin; Apc^Min/+V, Apc^Min/+ mice gavaged with vehicle solution mix of Tang juice and water; C57BL/6-Q, control mice gavaged with quercetin; C57BL/6-V, control mice gavaged with vehicle solution mix of Tang juice and water; Gastroc, gastrocnemeous; Gen, genotype; Int, interaction; M.E., main effect; Quad, quadriceps; vehicle, vehicle solution mix of Tang juice and water.