TABLE 1.
The effect of quercetin on cachexia-related symptoms in C57BL/6 and Min/+ mice1
| C57BL/6 |
ApcMin/+ |
P values for 2-factor ANOVA |
|||||
| Vehicle (n = 8) | Quercetin (n = 4) | Vehicle (n = 5) | Quercetin (n = 5) | G | T | G × T | |
| Spleen, mg | 81 ± 4.2a | 88 ± 1.6a | 435 ± 45b | 378 ± 18b | <0.01 | 0.23 | 0.23 |
| Heart, mg | 119 ± 12.7 | 113 ± 4.9 | 113 ± 9.6 | 100 ± 2.1 | 0.16 | 0.13 | 0.97 |
| Testes, mg | 196 ± 8.0a | 193 ± 7.2a | 142 ± 14b | 183 ± 11a | 0.01 | 0.11 | 0.02 |
| Tibia length, mm | 17.2 ± 0.1 | 17.3 ± 0.1 | 17.1 ± 0.1 | 17.1 ± 0.3 | 0.31 | 0.88 | 0.99 |
| Polyps, n | 1 ± 1.0a | 1 ± 0.7a | 28 ± 14b | 14 ± 10b | 0.01 | 0.20 | 0.20 |
1
Values are means ± SEs. Labeled means in a row without a common letter differ, P ≤ 0.05. Apc, adenomatous polyposis coli; G, genotype; T, treatment; vehicle, vehicle solution mix of Tang juice and water.