TABLE 3.
Influence of inflammation on mean plasma micronutrient status indicator concentrations in rural Nepalese children (n = 1000)1
| Indicator | No inflammation (n = 684) | Inflammation (n = 316) | P |
| Retinol, μmol/L | 1.07 (1.05, 1.09) | 0.97 (0.93, 0.99) | <0.0001 |
| β-Carotene,2 μmol/L | 0.12 (0.11, 0.13) | 0.09 (0.08, 0.10) | 0.0001 |
| α-Tocopherol, μmol/L | 12.4 (12.1, 12.6) | 11.8 (11.5, 12.1) | 0.008 |
| α-Tocopherol:cholesterol, μmol/mmol | 4.07 (4.00, 4.14) | 3.99 (3.90, 4.09) | 0.2 |
| 25(OH)D, nmol/L | 66.4 (65.0, 68.1) | 66.1 (64.2, 68.1) | 0.8 |
| PIVKA-II,2 μg/L | 0.92 (0.83, 1.01) | 1.05 (0.91, 1.20) | 0.1 |
| PLP, nmol/L | 25.2 (24.2, 26.2) | 20.9 (19.6, 22.3) | <0.0001 |
| Cobalamin,2 pmol/L | 225 (218, 238) | 238 (226, 251) | 0.05 |
| Folic acid,2 nmol/L | 23.7 (23.1, 24.4) | 23.1 (22.1, 24.1) | 0.3 |
| Ferritin,2 μg/L | 32.9 (31.4, 34.6) | 43.7 (40.5, 47.3) | <0.0001 |
| TfR,2 mg/L | 7.7 (7.5, 7.9) | 8.4 (8.1, 8.8) | <0.0001 |
| TfR:ferritin,2 μg/μg | 233 (219, 248) | 193 (175, 212) | 0.0009 |
| Total circulating selenium, μmol/L | 0.89 (0.87, 0.91) | 0.81 (0.85, 0.88) | <0.0001 |
| Total circulating copper, μmol/L | 22.4 (22.0, 22.8) | 25.7 (25.1, 23.8) | <0.0001 |
| Thyroglobulin,2 μg/L | 17.5 (16.6, 18.4) | 17.0 (15.7, 18.5) | 0.6 |
1
Values are means (95% CIs). Missing values: n = 1 for PIVKA-II and cobalamin, n = 2 for folic acid, n = 5 for ferritin and thyroglobulin, n = 1 for selenium and copper. PIVKA-II, protein induced in vitamin K absence; PLP, pyridoxal-5′-phosphate; TfR, transferrin receptor; 25(OH)D, 25-hydroxyvitamin D.
2
Geometric means and 95% CIs derived from the log10 scale are shown; t tests were performed on the log10-transformed data.