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. Author manuscript; available in PMC: 2014 Aug 20.
Published in final edited form as: Antivir Ther. 2013 Aug 20;18(6):793–802. doi: 10.3851/IMP2676

Table 1.

Clinical Characteristics

Total
N (%)
Measured
GFR
(mL/min)
Mean (SD)
Estimated GFR (mL/min) Mean (SD)
CKD-EPI MDRD Study Cockcroft-Gault
All patientsa 200 (100) 97 ± 31 89 ± 28 83 ± 27 89 ± 30
(mL/min per 1.732) 200 (100) 87 ± 26 80 ± 24 75 ± 23 80 ± 23
Age group, years
 ≤50 132 (66) 103 ± 31 95 ± 27 88 ± 26 96 ± 29
 >50 68 (34) 84 ± 28 77 ± 27 74 ± 26 76 ± 29
Sex
 Women 55 (28) 85 ± 30 79 ± 26 73 ± 23 85 ± 34
 Men 145 (73) 101 ± 31 93 ± 28 87 ± 27 91 ± 29
Race
 African Americans 104 (52) 97 ± 34 91 ± 31 86 ± 29 87 ± 32
 White or other 96 (48) 96 ± 28 87 ± 25 80 ± 24 92 ± 29
BMI group, kg/m2
 <22 35 (18) 83 ± 29 82 ± 28 77 ± 28 70 ± 23
 22-30 129 (65) 97 ± 31 90 ± 28 84 ± 26 89 ± 27
 >30 36 (18) 106 ± 33 92 ± 30 86 ± 28 109 ± 36
Hypertension b 60 (31) 96 ± 34 85 ± 27 80 ± 26 86 ± 28
Diabetes Mellitus 16 (8) 85 ± 26 81 ± 29 76 ± 26 80 ± 29
Hepatitis B 22 (11) 85 ± 25 80 ± 23 75 ± 21 81 ± 25
Hepatitis C 51 (26) 87 ± 27 86 ± 29 80 ± 27 84 ± 32
CD4 count group, cells/ulb
 <350 47 (25) 95 ± 30 88 ± 29 82 ± 27 87 ± 32
 ≥350 144 (75) 97 ± 32 90 ± 28 84 ± 27 91 ± 30
Viral load group, copies/mb
 Undetected 111 (61) 93 ± 32 86 ± 29 80 ± 27 86 ± 30
 <1000 57 (31) 106 ± 30 97 ± 26 90 ± 25 100 ± 30
 ≥1000 14 (8) 94 ± 32 90 ± 32 86 ± 29 80 ± 28
Tenofovir use/exposure
 Yes 125 (63) 97 ± 31 89 ± 28 83 ± 26 91 ± 31
 No 75 (38) 96 ± 33 89 ± 30 83 ± 29 87 ± 29
Source of HIV Transmission
 Injection 24 (12) 93 ± 27 92 ± 25 86 ± 23 88 ± 26
 Male-to-male 75 (38) 97 ± 30 92 ± 30 86 ± 29 89 ± 29
 Heterosexual 51 (26) 102 ± 32 89 ± 29 83 ± 27 96 ± 35
 Other 50 (25) 92 ± 34 84 ± 27 78 ± 25 83 ± 28

Note: Values are mean ± standard deviation or number (percentage).

a

p<0.001 for comparison of each kidney function estimate to measured GFR

b

5 patients had missing data for hypertension; 1 patient for diabetes mellitus, 9 patients for CD4 count and 18 patients for viral load

Tenofovir (Viread®)