Table 1.
Total N (%) |
Measured GFR (mL/min) Mean (SD) |
Estimated GFR (mL/min) Mean (SD) |
|||
---|---|---|---|---|---|
CKD-EPI | MDRD Study | Cockcroft-Gault | |||
All patientsa | 200 (100) | 97 ± 31 | 89 ± 28 | 83 ± 27 | 89 ± 30 |
(mL/min per 1.732) | 200 (100) | 87 ± 26 | 80 ± 24 | 75 ± 23 | 80 ± 23 |
Age group, years | |||||
≤50 | 132 (66) | 103 ± 31 | 95 ± 27 | 88 ± 26 | 96 ± 29 |
>50 | 68 (34) | 84 ± 28 | 77 ± 27 | 74 ± 26 | 76 ± 29 |
Sex | |||||
Women | 55 (28) | 85 ± 30 | 79 ± 26 | 73 ± 23 | 85 ± 34 |
Men | 145 (73) | 101 ± 31 | 93 ± 28 | 87 ± 27 | 91 ± 29 |
Race | |||||
African Americans | 104 (52) | 97 ± 34 | 91 ± 31 | 86 ± 29 | 87 ± 32 |
White or other | 96 (48) | 96 ± 28 | 87 ± 25 | 80 ± 24 | 92 ± 29 |
BMI group, kg/m2 | |||||
<22 | 35 (18) | 83 ± 29 | 82 ± 28 | 77 ± 28 | 70 ± 23 |
22-30 | 129 (65) | 97 ± 31 | 90 ± 28 | 84 ± 26 | 89 ± 27 |
>30 | 36 (18) | 106 ± 33 | 92 ± 30 | 86 ± 28 | 109 ± 36 |
Hypertension b | 60 (31) | 96 ± 34 | 85 ± 27 | 80 ± 26 | 86 ± 28 |
Diabetes Mellitus | 16 (8) | 85 ± 26 | 81 ± 29 | 76 ± 26 | 80 ± 29 |
Hepatitis B | 22 (11) | 85 ± 25 | 80 ± 23 | 75 ± 21 | 81 ± 25 |
Hepatitis C | 51 (26) | 87 ± 27 | 86 ± 29 | 80 ± 27 | 84 ± 32 |
CD4 count group, cells/ulb | |||||
<350 | 47 (25) | 95 ± 30 | 88 ± 29 | 82 ± 27 | 87 ± 32 |
≥350 | 144 (75) | 97 ± 32 | 90 ± 28 | 84 ± 27 | 91 ± 30 |
Viral load group, copies/mb | |||||
Undetected | 111 (61) | 93 ± 32 | 86 ± 29 | 80 ± 27 | 86 ± 30 |
<1000 | 57 (31) | 106 ± 30 | 97 ± 26 | 90 ± 25 | 100 ± 30 |
≥1000 | 14 (8) | 94 ± 32 | 90 ± 32 | 86 ± 29 | 80 ± 28 |
Tenofovir use/exposure | |||||
Yes | 125 (63) | 97 ± 31 | 89 ± 28 | 83 ± 26 | 91 ± 31 |
No | 75 (38) | 96 ± 33 | 89 ± 30 | 83 ± 29 | 87 ± 29 |
Source of HIV Transmission | |||||
Injection | 24 (12) | 93 ± 27 | 92 ± 25 | 86 ± 23 | 88 ± 26 |
Male-to-male | 75 (38) | 97 ± 30 | 92 ± 30 | 86 ± 29 | 89 ± 29 |
Heterosexual | 51 (26) | 102 ± 32 | 89 ± 29 | 83 ± 27 | 96 ± 35 |
Other | 50 (25) | 92 ± 34 | 84 ± 27 | 78 ± 25 | 83 ± 28 |
Note: Values are mean ± standard deviation or number (percentage).
p<0.001 for comparison of each kidney function estimate to measured GFR
5 patients had missing data for hypertension; 1 patient for diabetes mellitus, 9 patients for CD4 count and 18 patients for viral load
Tenofovir (Viread®)