TABLE 2.
Expression of mast cell-enriched genes in the control or GATA1 siRNA-treated BMMCs
| Gene | Entrez full name | Gene ID | Fold change | P | Reference |
|---|---|---|---|---|---|
| Gata1 | GATA binding protein 1 | 14460 | –4.88 | 6.8E–15 | |
| Mast cell protease genes | |||||
| Mcpt2 | Mast cell protease 2 | 17225 | –1.61 | 1.4E–03 | |
| Mcpt4 | Mast cell protease 4 | 17227 | –1.91 | 2.0E–05 | |
| Cma2 | Chymase 2, mast cell | 545055 | –1.57 | 2.3E–03 | |
| Tpsab1 | Tryptase alpha/beta 1 (Tpsab1) | 100503895 | –2.22 | 5.2E–07 | |
| Tpsb2 | Tryptase beta 2 | 17229 | –1.53 | 3.6E–03 | |
| Cpe | Carboxypeptidase E (Cpe) | 12876 | 1.91 | 4.0E–05 | |
| Mast cell proteoglycan genes | |||||
| Prg2 | Proteoglycan 2 | 19074 | –1.46 | 8.9E–03 | 32 |
| Agrn | Agrin | 11603 | –2.19 | 3.0E–02 | 32 |
| Gpc2 | Glypican 2 (cerebroglycan) | 71951 | 4.00 | 3.3E–02 | 32 |
| Chad | Chondroadherin | 12643 | 1.39 | 3.5E–02 | 32 |
| Gpc1 | Glypican 1 | 14733 | 1.35 | 3.8E–02 | 32 |
| Other mast cell-related genes | |||||
| CtsD | Cathepsin D | 13033 | 1.40 | 2.1E–02 | 33 |
| Ctsg | Cathepsin G | 13035 | –1.35 | 3.7E–02 | 34 |
| Timp3 | Tissue inhibitor of metalloproteinase 3 | 21859 | 1.29 | 1.9E–02 | 34 |
| pld2 | Phospholipase D family, member 2 | 18806 | –1.45 | 1.0E–02 | 35 |
| Dusp14 | Dual specificity phosphatase 14 | 56405 | 1.71 | 4.5E–04 | 34 |
| Maob | Monoamine oxidase B | 109731 | –1.98 | 1.0E–05 | 34 |
| Trib2 | Tribbles homolog 2 (Drosophila) | 217410 | –1.43 | 4.8E–02 | 34 |
| Trib3 | Tribbles homolog 3 | 228775 | –1.41 | 1.8E–02 | 36 |
| C3 | Complement component 3 (C3) | 12266 | 1.48 | 2.2E–16 | 37 |
| C5ar1 | Complement component 5a receptor 1 | 12273 | 1.47 | 1.2E–02 | 38 |
| Grk5 | G protein-coupled receptor kinase 5 | 14773 | –1.64 | 8.6E–04 | 39 |
| Tlr1 | Toll-like receptor 1 | 21897 | 1.37 | 3.2E–02 | 40 |
| Tlr2 | Toll-like receptor 2 | 24088 | 1.24 | 2.1E–06 | 40 |
| myd88 | Myeloid differentiation primary response gene 88 | 17874 | 1.10 | 3.3E–02 | 40 |
| Il13 | Interleukin-13 | 16163 | –1.42 | 1.6E–02 | 41 |
| fgf2 | Fibroblast growth factor 2 | 14173 | –2.05 | 2.8E–45 | 42 |
| Ccr2 | Chemokine (C-C motif) receptor 2 | 12772 | 1.61 | 1.3E–03 | 43 |
| Cx3cr1 | Chemokine (C-X3-C) receptor 1 | 13051 | –1.87 | 7.0E–05 | 44 |
| Fyb | FYN binding protein | 23880 | –1.54 | 3.3E–03 | 45 |
| Orai1 | ORAI calcium release-activated calcium modulator 1 | 109305 | 1.44 | 1.3E–02 | 46 |
| Mt1 | Metallothionein 1 | 17748 | 1.03 | 1.0E–02 | 34 |
| Fst | Follistatin | 14313 | –1.34 | 4.8E–02 | 34 |
| Nlrp3 | NLR family, pyrin domain containing 3 | 216799 | –1.45 | 2.3E–02 | 47 |
| Socs3 | Suppressor of cytokine signaling 3 | 12702 | 1.38 | 2.6E–02 | 48 |
| CD52 | CD52 antigen | 23833 | 1.75 | 1.9E–04 | 49 |
| CD69 | CD69 antigen | 12515 | 1.44 | 1.2E–02 | 50 |