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Other mammalian pre-mRNA 3′ processing factors. (A) Domain organization of human symplekin, PAP, and PABPN1. (B) Crystal structure of the symplekin-Ssu72-RNAP II CTD peptide complex (PDB ID no. 3O2Q [153]). (C) Conformation of the RNAP II CTD peptide in the active site of Ssu72. (D) Crystal structure of the RRM domain dimer of PABPN1 (PDB ID no. 3B4M [192]). (E) Crystal structure of yeast Pap1 in complex with ATP and an oligo(A) sequence (PDB ID no. 2Q66 [176]).
