TABLE 1.
Administration Schedule for Dynamic Infusion (DI) METH with Escalating Dosage.
Monday | Tuesday | Wednesday | Thursday | Friday | |
---|---|---|---|---|---|
Week 1 | 0.125 | 0.125 | 0.125 | 2 × 0.125 | 2 × 0.125 |
Week 2 | 0.125 | 0.1875 | 0.1875 | 2 × 0.1875 | 2 × 0.1875 |
Week 3 | 0.1875 | 0.25 | 0.25 | 2 × 0.25 | 2 × 0.25 |
Week 4 | 0.25 | 0.375 | 0.375 | 2 × 0.375 | 2 × 0.375 |
Week 5 | 0.375 | 0.5 | 0.5 | 2 × 0.5 | 2 × 0.5 |
Week 6 | 0.5 | 2 × 0.5 | 2 × 0.5 | 2 × 0.5 | 2 × 0.5 |
Week 7 | 0.5 | 2 × 0.5 | 2 × 0.5 | 2 × 0.5 | 2 × 0.5 |
Week 8 | 0.5 | 2 × 0.5 | 2 × 0.5 |
A single DI METH injection/day is indicated by the dosage (mg/kg); Two DI injections/day are indicated 2 × dosage. On days when two DI METH injections were delivered, the inter-injection interval was 4 h.