TABLE II.
Administration Schedule for Dynamic Infusion (DI) METH Exposures for Long Term METH and METH Challenge.
Group | Long Term | METH Challenge |
---|---|---|
1 | saline | saline |
2 | saline | DI METH 2 × 0.5 mg/kg |
3 | DI METH | Saline |
4 | DI METH | DI METH 2 × 0.5 mg/kg |
On the 3rd day of Week 8, all groups were administered the METH Challenge and euthanized at 1 h after their 2nd DI METH – or saline injection.