FIG 9.

Assessment of soluble biomarkers in wild AGMs from the Gambia. No significant increase in the markers associated with increased death in HIV-infected patients was observed in SIV-infected AGMs from the Gambia. (a) sCD14; (b) IL-6; (c) C-reactive protein. Significantly higher levels of D dimer were observed in SIV-infected AGMs, which were due to an age-related increase (d). Infant AGMs are illustrated as open circles and squares; juvenile AGMs are illustrated as gray circles and squares; adult AGMs are shown as black circles and squares. Samples collected from female AGMs are illustrated as circles (○); samples collected from male AGMs are shown as squares (□); the samples from acutely infected adult females (defined as having high viral loads and negative serologies) are illustrated as open circles with enhanced margins; the sample collected from an acutely infected juvenile female is illustrated as V; finally, two samples from juvenile monkeys with high viral loads but seropositive results (probably postacutely infected) are shown as half-empty symbols. P values were calculated by the Mann-Whitney U test.