Differentially expressed genes in NEO, CR, and CT cells at 1 min (constitutive changes). (A) Venn diagrams of differentially expressed (downregulated and upregulated) genes in NEO, CT, and CR cells. (B) Heat map of selected top genes constitutively altered (1 min) after recombinant receptor expression. Left, NEO versus CT; middle, NEO versus CR; right, CT versus CR. Genes are clustered using row-normalized signals and mapped to the [−1,1] interval (shown in scales beneath each heat map). Red and blue represent high and low expression values, respectively.