TABLE 3.
Significantly affected functional categoriesa
| Functional category |
P valueb (1–60 min) |
||
|---|---|---|---|
| CR | CT | NEO | |
| Cellular growth and proliferation | 1.35E−05–6.15E−02 | 1.28E−03–1.27E−01 | 1.26E−04–1.21E−01 |
| Hematological system development and function | 4.99E−05–7.25E−02 | 1.28E−03–1.27E−01 | 6.74E−03–1.21E−01 |
| Cellular development | 4.41E−05–7.25E−02 | 4.05E−03–1.27E−01 | 9.43E−03–1.21E−01 |
| Cellular movement | 4.43E−05–7.25E−02 | 2.52E−02–1.27E−01 | 9.58E−03–1.21E−01 |
| Cell death | 1.01E−04–7.25E−02 | 6.54E−03–1.27E−01 | 1.58E−02–1.21E−01 |
| Cell-mediated immune response | 5.25E−04–7.25E−02 | 1.28E−03–1.27E−01 | 2.34E−02–1.21E−01 |
| Cell cycle | 5.46E−04–6.52E−02 | 6.81E−02–1.27E−01 | 2.34E−02–1.21E−01 |
| Lipid metabolism | 3.12E−02–5.96E−02 | 4.19E−02–1.27E−01 | 3.66E−02–1.21E−01 |
| Antigen presentation | 9.96E−03–1.27E−01 | 6.51E−02–1.21E−0 | |
| Immune cell trafficking | 5.96E−02–5.96E−02 | 1.28E−03–1.27E−01 | 6.51E−02–1.21E−01 |
a
Significant perturbations in biological function categories were identified using the Ingenuity Pathway Analysis biological function analysis tool. Differentially expressed genes in each cell type were uploaded into IPA for analysis.
b
The P value is corrected for multiple tests.