TABLE 5.
Conservation of the 3′ consensus sequence (3′CS) in the NSP1 gene of RVA from GenBank data
| Straina | Host | Genotype |
3′CS (UGU GACC) | GenBank accession no. | Reference (PubMed ID) | |
|---|---|---|---|---|---|---|
| G/P | NSP1 | |||||
| Wild type | ||||||
| EB-mouse | Murine | G16P[16] | A7 | Conserved | This study | This study |
| B4106 | Human | G3P[14] | A9 | Conserved | AY740735 | 16571797 |
| DRC86 | Human | G8P[6] | A2 | Conserved | DQ005119 | 16672410 |
| DRC88 | Human | G8P[8] | A2 | Conserved | DQ005108 | 16672410 |
| B4633 | Human | G12P[8] | A1 | Conserved | DQ146644 | 17166908 |
| Dhaka12 | Human | G12P[6] | A1 | Conserved | DQ146666 | 17166908 |
| Dhaka16 | Human | G1P[8] | A1 | Conserved | DQ492675 | 17166908 |
| Dhaka25 | Human | G12P[8] | A1 | Conserved | DQ146655 | 17166908 |
| N26 | Human | G12P6] | A2 | Conserved | DQ146688 | 17166908 |
| RV161 | Human | G12P[6] | A2 | Conserved | DQ490540 | 17166908 |
| RV176 | Human | G12P[6] | A2 | Conserved | DQ490557 | 17166908 |
| Matlab13 | Human | G12P[6] | A1 | Conserved | DQ146677 | 17166908 |
| B3458 | Human | G9P[8] | A1 | Conserved | EF990709 | 18216098 |
| TB-Chen | Human | G2P[4] | A2 | Conserved | AY787647 | 18329063 |
| B1711 | Human | G6P[6] | A2 | Conserved | EF554088 | 18796733 |
| RC-18-08 | Antelope | G6P[14] | A11 | Conserved | FJ495130 | 19153225 |
| B383 | Bovine | G15P[11] | A13 | Conserved | FJ347117 | 19153225 |
| Chubut | Guanaco | G8P[14] | A3 | Conserved | FJ347106 | 19153225 |
| Rio_Negro | Guanaco | G8P[1] | A11 | Conserved | FJ347128 | 19153225 |
| GR10924/99 | Human | G9P[6] | A2 | Conserved | FJ183357 | 19264638 |
| PAH136 | Human | G3P[9] | A3 | Conserved | GU296410 | 20409385 |
| PAI58 | Human | G3P[9] | A3 | Conserved | GU296411 | 20409385 |
| BA222 | Feline | G3P[9] | A3 | Conserved | GU827412 | 21228122 |
| mani-265/07 | Human | G10P[6] | A3 | Conserved | HM348718 | 21884295 |
| MWI/1473 | Human | G8P[4] | A2 | Conserved | HQ657133 | 21915879 |
| 3133WC | Human | G12P[4] | A1 | Conserved | HQ657144 | 21915879 |
| 3176WC | Human | G12P[6] | A1 | Conserved | HQ657155 | 21915879 |
| 3203WC | Human | G2P[4] | A2 | Conserved | HQ657166 | 21915879 |
| 2371WC-B | Human | G9P[8] | A1 | Conserved | JN013975 | 22019521 |
| 2371WC-A | Human | G9P[8] | A2 | Conserved | JN013974 | 22019521 |
| 1603 | Bovine | G6P[5] | A3 | Conserved | JN831204 | 22541163 |
| 1604 | Bovine | G8P[1] | A3 | Conserved | JN831215 | 22541163 |
| 1605 | Bovine | G6P[5] | A3 | Conserved | JN831226 | 22541163 |
| E30 | Equine | G3P[12] | A10 | Conserved | JF712572 | 22190012 |
| E403 | Equine | G14P[12] | A10 | Conserved | JF712583 | 22190012 |
| E4040 | Equine | G14P[12] | A10 | Conserved | JN872871 | 22190012 |
| 04V2024 | Equine | G14P[12] | A10 | Conserved | JN903515 | 22190012 |
| EqRV-SA1 | Equine | G14P[12] | A10 | Conserved | JQ345493 | 22190012 |
| Tissue culture | ||||||
| EB-tc | Murine | G16P[16] | A7 | UGU GAACC | This study | This study |
| EB-tc-ll40 | Murine | G16P[16] | A7 | UGU GAUCC | This study | This study |
| EB-tc-cc40 | Murine | G16P[16] | A7 | UGU GACACC | This study | This study |
| KU | Human | G1P[8] | A1 | UGU GAACC | AB022769 | 10481750 |
| K9 | Canine | G3P[3] | A9 | UGU GAACC | AF111946 | 10481750 |
| RV198-95 | Canine | G3P[3] | A9 | UGU GAACC | HQ661140 | 21609783 |
| SA11-4F | Simian | G3P[2] | A5 | UGU GAACC | AF290883 | 11160712 |
| SA11-30-19 | Simian | G3P[2] | A5 | UGU GAACC | AF290881 | 11160712 |
| SA11-N2 | Simian | G3P[2] | A5 | UGU GAACC | JN827248 | 23263646 |
| SA11-N5 | Simian | G3P[2] | A5 | UGU GAACC | JQ688677 | 23263646 |
| L338 | Equine | G13P[18] | A6 | UGU GAACC | JF712561 | 22190012 |
| RRV-AUU | Simian | G3P[3] | A9 | UGA UUCC | AY117049 | 15372078 |
| RRV-CCUU | Simian | G3P[3] | A9 | UGCC UUCC | AY117050 | 15372078 |
| RRV-CUU | Simian | G3P[3] | A9 | UGC UUCC | AY117051 | 15372078 |
| RRV-U | Simian | G3P[3] | A9 | UG UUCC | AY117052 | 15372078 |
| RRV-UU | Simian | G3P[3] | A9 | UGU UUCC | AY117053 | 15372078 |
| 10V0112H5 | Avian | G23P[37] | A16 | UAU GACC | JX204817 | 23052396 |
| 03V0002E10 | Avian | G22P[35] | A16 | UAU GACC | JX204828 | 23052396 |
| RotaTeq-BrB-9 | Vaccine | G4P[5] | A3 | Conserved | GU565091 | 20451234 |
| RotaTeq-SC2-9 | Vaccine | G2P[5] | A3 | Conserved | GU565069 | 20451234 |
| RotaTeq-WI78-8 | Vaccine | G3P[5] | A3 | Conserved | GU565080 | 20451234 |
| RotaTeq-WI79-4 | Vaccine | G6P[8] | A3 | Conserved | GU565047 | 20451234 |
| RotaTeq-WI79-9 | Vaccine | G1P[5] | A3 | Conserved | GU565058 | 20451234 |
| B10 | Human | G3P[2] | A5 | Conserved | HM627559 | 21035567 |
| DS-1 | Human | G2P[4] | A2 | Conserved | HQ650120 | 21600242 |
| PA260-97 | Human | G3P[3] | A15 | Conserved | HQ661118 | 21609783 |
| RV52-96 | Canine | G3P[3] | A9 | Conserved | HQ661129 | 21609783 |
| 30-96 | Lapine | G3P[14] | A9 | Conserved | DQ205225 | 16571797 |
| RRV | Simian | G3P[3] | A9 | Conserved | AY117048 | 15372078 |
| PO-13 | Avian | G18P[17] | A4 | Conserved | AB009633 | 11325467 |
| RF | Bovine | G6P[1] | A3 | Conserved | M22308 | 2823457 |
| UK | Bovine | G6P[5] | A3 | Conserved | Not available | 15372078 |
a
The EB prefix indicates the murine RV EB strain used in this study. EB-mouse is the murine RV EB strain passaged by mouse pups. EB-tc is the murine RV EB strain passaged by cell cultures except for ll40 and cc40.