FIG 8.

Sialostatin L2 does not affect A. phagocytophilum load during infection. (A) Bacterial loads following intradermal infection of A. phagocytophilum in the presence of sialostatin L2 (SL2) (10 μg/injection). Sialostatin L2 was injected 5 h prior to, during, and 5 h after pathogen inoculation. Bacterial loads were measured at 24 h postinjection by quantitative RT-PCR. (B) Bacterial loads in the peripheral blood of mice following intraperitoneal infection of A. phagocytophilum in the presence of SL2 (10 μg/injection). *, P < 0.05 (Student's t test); NS, not significant.