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Histology after the treatments of colonic loops for Fig. 4. CPE (50 μg/ml) or CPE (50 μg/ml) plus MAb1 produced similar microscopic lesions, characterized mainly by severe mucosal necrosis and occasional congestion/hemorrhage of the lamina propria. Heat-inactivated CPE (50 μg/ml), CPE (50 μg/ml) plus MAb3, BSA, or buffer produced no histologic lesions.
