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. 2014 Jun;82(6):2266–2275. doi: 10.1128/IAI.01528-13

TABLE 2.

Sensitivities of wild-type C. jejuni, isogenic deletion mutants, and corresponding complemented strains to H2O2, cumene hydroperoxide, or menadione bisulfite

Functional category and strain Diam (mm) of zone of inhibition with oxidanta
H2O2 CHP MND
C. jejuni NCTC11168 19.08 ± 0.19 24.50 ± 0.22 31.63 ± 0.36
Detoxification
    Δcj0358 16.44 ± 0.72* 23.50 ± 0.53 29.63 ± 0.80
    Δcj0358+cj0358 17.40 ± 0.40 22.50 ± 0.52 31.93 ± 1.13
    ΔkatAb 28.85 ± 0.87* 26.43 ± 0.47 29.85 ± 1.39
    ΔkatA+katAb 10.83 ± 1.24* 23.83 ± 0.17 31.00 ± 1.20
    ΔahpCb 17.23 ± 0.50* 34.87 ± 0.79* 29.05 ± 1.81
    ΔahpC+ahpCb 18.45 ± 0.10 25.40 ± 0.34 28.38 ± 0.39
    ΔsodBb 22.10 ± 0.35* 30.75 ± 3.53* 38.28 ± 1.96*
    ΔsodB+sodBb 21.78 ± 0.33 25.40 ± 0.17 37.50 ± 2.62
    Δcj1386c 25.21 ± 0.28* 25.67 ± 0.76 35.04 ± 1.36
    Δcj1386+cj1386c 19.90 ± 0.57 24.20 ± 0.51 37.30 ± 0.76
Cation transport/binding
    ΔchaN 17.37 ± 0.30 21.47 ± 0.17* 29.83 ± 0.61
    ΔchaN+chaN 17.26 ± 0.75 22.82 ± 0.66 34.08 ± 1.97
    ΔexbB1 16.90 ± 0.31* 23.13 ± 0.64 28.30 ± 0.58
    ΔexbB1+exbB1 17.33 ± 0.60 22.63 ± 0.37 32.90 ± 1.16
    ΔtonB2 21.10 ± 0.46* 26.47 ± 0.67 33.07 ± 1.39
Energy metabolism
    ΔacnB 21.22 ± 0.45* 23.28 ± 0.24 36.28 ± 0.72
    ΔacnB+acnB 20.27 ± 0.25 21.33 ± 0.44 33.44 ± 1.49
Surface structures
    ΔflhB 19.80 ± 0.44 23.18 ± 0.32 36.53 ± 1.86*
    ΔflhB+flhB 18.18 ± 0.76 20.86 ± 0.82 32.15 ± 0.99
    ΔflgD 20.47 ± 0.47 26.27 ± 0.36 36.50 ± 0.31*
    ΔflgD+flgD 18.40 ± 0.31 23.60 ± 0.80 31.70 ± 0.58
    ΔflgH 21.00 ± 0.42* 26.55 ± 0.55 37.00 ± 1.30*
    ΔflgH+flgH 19.07 ± 0.37 23.37 ± 0.23 32.33 ± 1.19
    ΔflgI 21.35 ± 0.43* 26.00 ± 0.30 35.38 ± 1.89
    ΔflgI+flgI 18.95 ± 0.34 23.95 ± 0.21 31.70 ± 1.13
    ΔflgK 21.53 ± 0.13* 26.13 ± 0.46 34.90 ± 2.04
    ΔflgK+flgK 19.67 ± 0.17 24.73 ± 0.15 31.10 ± 0.49
    ΔflgL 21.00 ± 0.23* 25.08 ± 0.32 34.67 ± 1.73
    ΔflgL+flgL 18.33 ± 1.17 21.25 ± 0.12 30.67 ± 0.10
    ΔpseB 20.50 ± 0.32 25.92 ± 0.53 35.95 ± 1.40*
    ΔpseB+pseB 18.95 ± 1.13 23.67 ± 1.20 26.94 ± 2.96
    ΔflgP 21.63 ± 1.24* 26.25 ± 0.86 35.25 ± 2.21
    ΔflgP+flgP 19.94 ± 0.59 25.74 ± 0.62 33.08 ± 1.26
    ΔflgR 20.47 ± 0.75 25.63 ± 0.34 36.78 ± 1.35*
    ΔflgR+flgR 17.90 ± 0.61 22.17 ± 0.35 32.83 ± 0.87
Hypothetical unknown proteins
    Δcj0260c 17.42 ± 0.19 21.67 ± 0.44* 30.87 ± 0.75
    Δcj0260c+cj0260c 17.50 ± 0.35 22.83 ± 0.57 30.85 ± 0.35
    Δcj0344 20.92 ± 0.14* 23.92 ± 0.45 33.33 ± 1.01
    Δcj0344+cj0344 18.12 ± 0.73 21.25 ± 1.24 30.36 ± 1.33
    Δcj1159c 19.71 ± 0.90 22.25 ± 0.40* 30.42 ± 0.72
Miscellaneous
    Δcj0062c 21.73 ± 0.21* 26.00 ± 0.39 35.67 ± 0.33
    Δcj0062c+cj0062c 19.44 ± 0.39 25.20 ± 0.50 33.63 ± 1.80
    Δcj0947c 23.94 ± 1.20* 26.44 ± 0.80 43.00 ± 3.76*
    Δcj0947c+cj0947c 20.66 ± 1.50 25.55 ± 0.50 32.33 ± 0.19
    Δcj1388 21.17 ± 0.41* 25.38 ± 0.61 35.33 ± 2.20
    Δcj1623 18.33 ± 0.50 21.95 ± 0.19* 34.78 ± 2.50
    Δcj1623+cj1623 17.44 ± 0.49 22.70 ± 0.39 32.63 ± 1.44
    ΔpstC 20.75 ± 0.31* 27.25 ± 1.00* 32.33 ± 1.24
    ΔpstC+pstC 20.60 ± 0.25 25.30 ± 0.41 36.84 ± 1.79
a

The diameter of the zone of inhibition is represented as the mean clear zone ± standard error for each strain after exposure to 10 μl of 3% H2O2, 3% cumene hydroperoxide (CHP), or 90 mM menadione bisulfite (MND). Each experiment was repeated in quadruplicate. Values were considered significant (*) at a P value of <0.001 using Bayesian statistical analysis.

b

Data are from reference 16.

c

Data are from reference 15.