Table 2.
Toxicity details
| Patient/KPS/RPA | Age/gender | Histology/number of additional lesions treated | Location/size (cc) | GK dose/prior WBRT | Local failure/neurologic Death | Toxicity | Management |
|---|---|---|---|---|---|---|---|
| 1 90/II | 73/male | Non-small cell lung cancer/1 | Pons and midbrain/1.4 | 17 Gy/no | No/yes | Grade III. severe diplopia and dysphagia | Long term steroids provided minimal relief |
| 2 70/II | 57/female | Ovarian/1 | Midbrain/1.8 | 18 Gy/no | No/no | Grade III. Severe diplopia requiring continuous closure of left eye | Steroids provided little relief. She was unable to discontinue their use. She was offered tarsorrhaphy although she refused |
| 3 70/II | 59/male | Adenocarcinoma of unknown primary/0 | Pons/3.2 | 18 Gy/no | No/yes | Grade III. Suspected Radiation Necrosis. Mild ataxia and diplopia | Bevacizumab, complete resolution of symptoms |
| 4 80/II | 57/male | Non-small cell lung cancer/0 | Pons/3.5 | 18 Gy/no | No/no | Grade II. suspected radiation necrosis and ataxia | Low dose steroids provided minimal relief |