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. Author manuscript; available in PMC: 2014 May 13.
Published in final edited form as: J Neurooncol. 2014 Feb 7;117(1):167–174. doi: 10.1007/s11060-014-1373-x

Table 2.

Toxicity details

Patient/KPS/RPA Age/gender Histology/number of additional lesions treated Location/size (cc) GK dose/prior WBRT Local failure/neurologic Death Toxicity Management
1 90/II 73/male Non-small cell lung cancer/1 Pons and midbrain/1.4 17 Gy/no No/yes Grade III. severe diplopia and dysphagia Long term steroids provided minimal relief
2 70/II 57/female Ovarian/1 Midbrain/1.8 18 Gy/no No/no Grade III. Severe diplopia requiring continuous closure of left eye Steroids provided little relief. She was unable to discontinue their use. She was offered tarsorrhaphy although she refused
3 70/II 59/male Adenocarcinoma of unknown primary/0 Pons/3.2 18 Gy/no No/yes Grade III. Suspected Radiation Necrosis. Mild ataxia and diplopia Bevacizumab, complete resolution of symptoms
4 80/II 57/male Non-small cell lung cancer/0 Pons/3.5 18 Gy/no No/no Grade II. suspected radiation necrosis and ataxia Low dose steroids provided minimal relief