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. 2012 Feb 13;3(4):396–401. doi: 10.1111/j.2040-1124.2012.00198.x

Table 2.  Factors affecting glycated hemoglobin as determined by the multiple linear regression analysis.

Insulin monotherapy Insulin + OAD
GPs Specialists GPs Specialists
β (95% CI) P β (95% CI) P β (95% CI) P β (95% CI) P
Age −0.11 (−0.22 to −0.005) 0.002 −0.17 (−0.04 to −0.001) 0.04 −0.23 (−0.04 to 0.02) 0.000 −0.04 (−0.04 to 0.03) 0.73
Male sex −0.04 (−0.140 to 0.043) 0.30 0.007 (−0.19 to 0.21) 0.93 −0.0002 (−0.12 to 0.12) 1.00 0.009 (−0.31 to 0.33) 0.95
BMI 0.03 (−0.015 to 0.035) 0.43 −0.1 (−0.09 to 0.02) 0.25 0.08 (−0.006 to 0.06) 0.10 0.17 (−0.05 to 0.17) 0.27
Total insulin dose 0.13 (0.004 to 0.14) 0.001 0.32 (0.01 to 0.05) 0.001 0.03 (−0.005 to 0.008) 0.62 0.06 (−0.02 to 0.03) 0.70
Use of human (not analog) insulin 0.01 (−0.09 to 0.13) 0.73 −0.09 (−0.34 to 0.11) 0.31 0.11 (0.02 to 0.31) 0.02 −0.1 (−0.45 to 0.20) 0.45
Type of insulin
 Basal 0.07 (−0.05 to 0.48) 0.11 0.08 (−0.31 to 0.75) 0.41 0.08 (−0.15 to 0.58) 0.25 0.02 (−0.85 to 0.96) 0.90
 Premixed 0.11 (0.07 to 0.44) 0.006 0.16 (−0.01 to 0.70) 0.06 0.05 (−0.20 to 0.44) 0.46 −0.15 (−1.05 to 0.35) 0.32
 Bolus −0.004 (−0.28 to 0.26) 0.93 −0.01 (−0.66 to 0.57) 0.89 0.06 (−0.19 to 0.66) 0.28 −0.02 (−1.12 to 0.94) 0.86
 Basal–bolus −0.05 (−0.44 to 0.10) 0.21 −0.15 (−0.89 to 0.05) 0.08 0.04 (−0.35 to 0.74) 0.49 −0.19 (−2.24 to −9.78) 0.14
 Premixed‐bolus 0.005 (−0.39 to 0.44) 0.91 0.58 (−0.84 to 0.48) 0.58 −0.1 (−1.90 to 0.30) 0.15 0.15 (−0.60 to 2.13) 0.27
No. combined OAD −0.03 (−0.88 to 0.68) 0.81 0.44 (−0.88 to 2.93) 0.29
Type of OAD
 Glinide −0.09 (−1.11 to 0.56) 0.52 0.09 (−0.94 to 1.37) 0.41
 SU 0.04 (−0.26 to 0.42) 0.66 −0.12 (−1.00 to 0.57) 0.59
 BG −0.09 (−0.63 to 0.19) 0.29 0.33 (−0.18 to 1.33) 0.13
 α‐GI −0.06 (−0.39 to 0.20) 0.52 0.22 (−0.31 to 1.05) 0.28
 TZD 0.11 (−0.18 to 0.79) 0.22 −0.03 (−1.17 to 1.04) 0.90

α‐GI, α‐glucosidase inhibitor; β, standard regression coefficiency; BG, biguanide; BMI, body mass index; CI, confidence interval; GP, general practitioner; OAD, oral antidiabetic; SU, sulfonylurea; TZD, thiazolidinedione.