Table 1. Cardiovascular and metabolic outcomes.
| EQW (n = 340) | EBID (n = 338) | P‐value for treatment comparison | |||
|---|---|---|---|---|---|
| Baseline | Change from baseline | Baseline | Change from baseline | ||
| Total cholesterol (mg/dL) | 182.08 (2.11) | −9.41 (1.96)‡ | 183.97 (2.12) | −8.10 (2.04)‡ | 0.609 |
| HDL (mg/dL) | 48.83 (0.68) | −0.11 (0.41) | 48.69 (0.69) | −0.48 (0.43) | 0.476 |
| LDL (mg/dL) | 102.65 (1.84) | −7.30 (1.48)‡ | 104.67 (1.83) | −8.13 (1.53)‡ | 0.653 |
| Triglycerides (mg/dL)† | 136.95 (4.00) | 0.97 (0.02) | 136.57 (3.77) | 0.97 (0.03) | 0.807 |
| Heart rate (b.p.m.) | 76.48 (0.52) | 3.03 (0.53)‡ | 76.86 (0.52) | 0.77 (0.56) | 0.001 |
| Systolic blood pressure (mmHg) | 131.09 (0.84) | −5.41 (0.82)‡ | 131.59 (0.84) | −5.38 (0.86)‡ | 0.974 |
| Diastolic blood pressure (mmHg) | 78.80 (0.51) | −1.62 (0.52)§ | 79.51 (0.51) | −2.26 (0.55)‡ | 0.349 |
| hsCRP (mg/dL)† | 0.13 (0.01) | 0.85 (0.06) | 0.13 (0.01) | 0.78 (0.05) | 0.368 |
| Urinary albumin‐to‐creatinine ratio† | 0.02 (0.00) | 0.78 (0.05) | 0.02 (0.00) | 0.72 (0.05) | 0.370 |
| Waist‐to‐hip ratio | 0.93 (0.00) | 0.00 (0.00) | 0.94 (0.00) | 0.00 (0.00) | 0.364 |
Data are presented as least‐squares (LS) mean (standard error) unless otherwise noted. †Geometric mean is presented at baseline and the geometric LS mean (standard error) ratio of week 26 to baseline is presented as change from baseline. ‡P < 0.001, difference from baseline; §P = 0.002, difference from baseline. b.p.m., Beats per minute; HDL, high density lipoprotein; hsCRP, high‐sensitivity C‐reactive protein; LDL, low density lipoprotein.