Table 2. Odds ratios for 5‐year incidence of diabetes mellitus.
n | Cases | Multivariate‐adjusted* | HbA1c‐adjusted† | |||
---|---|---|---|---|---|---|
OR | 95% CI | OR | 95% CI | |||
Men | ||||||
Age (years) | ||||||
46–55 (reference) | 533 | 22 | 1 | 1 | ||
56–65 | 1257 | 99 | 2.25 | 1.37–3.68 | 1.84 | 1.09–3.09 |
66–75 | 1286 | 111 | 2.64 | 1.60–4.37 | 2.23 | 1.32–3.78 |
Body mass Index‡ | ||||||
1st quartile (reference) | 769 | 44 | 1 | 1 | ||
2nd quartile | 766 | 55 | 1.30 | 0.86–1.98 | 1.35 | 0.87–2.10 |
3rd quartile | 771 | 63 | 1.59 | 1.06–2.41 | 1.51 | 0.97–2.33 |
4th quartile | 770 | 70 | 1.73 | 1.15–2.62 | 1.51 | 0.98–2.34 |
Smoking | ||||||
Never (reference) | 1273 | 69 | 1 | 1 | ||
Past | 817 | 68 | 1.52 | 1.06–2.17 | 1.16 | 0.80–1.69 |
Current (<20/day) | 372 | 35 | 2.00 | 1.29–3.10 | 1.76 | 1.11–2.80 |
Current (≥20/day) | 614 | 60 | 2.29 | 1.56–3.35 | 1.72 | 1.14–2.59 |
Alcohol intake | ||||||
Non‐drinker (reference) | 1009 | 74 | 1 | 1 | ||
1st tertile | 515 | 29 | 0.85 | 0.54–1.34 | 0.76 | 0.47–1.23 |
2nd tertile | 652 | 56 | 1.22 | 0.84–1.78 | 1.12 | 0.76–1.67 |
3rd tertile | 900 | 73 | 1.07 | 0.75–1.52 | 1.01 | 0.69–1.47 |
Family history of diabetes (+) | 291 | 46 | 2.73 | 1.91–3.91 | 2.41 | 1.64–3.55 |
Physical activity (leisure time; active) | 795 | 61 | 0.98 | 0.72–1.35 | 1.04 | 0.74–1.45 |
Walking | ||||||
<0.5 h/day (reference) | 370 | 36 | 1 | 1 | ||
0.5–0.9 h/day | 627 | 47 | 0.74 | 0.46–1.18 | 0.64 | 0.39–1.06 |
1–1.9 h/day | 602 | 48 | 0.81 | 0.50–1.32 | 0.75 | 0.45–1.27 |
≥2 h/day | 1477 | 101 | 0.76 | 0.49–1.19 | 0.60 | 0.36–0.97 |
Physical activity (daily) | ||||||
Light (reference) | 420 | 37 | 1 | 1 | ||
Moderate | 1346 | 104 | 0.95 | 0.62–1.44 | 0.87 | 0.55–1.37 |
Slightly heavy | 1106 | 80 | 0.99 | 0.62–1.58 | 0.98 | 0.59–1.61 |
Heavy | 204 | 11 | 0.73 | 0.34–1.56 | 0.64 | 0.29–1.41 |
Hypertension (+) | 1421 | 123 | 1.20 | 0.90–1.60 | 1.27 | 0.93–1.72 |
Coffee intake | ||||||
<1 cups/day (reference) | 1795 | 139 | 1 | 1 | ||
1–1.9 cups/day | 629 | 47 | 1.01 | 0.71–1.43 | 0.98 | 0.67–1.42 |
2–2.9 cups/day | 369 | 26 | 0.98 | 0.63–1.54 | 0.93 | 0.58–1.50 |
≥3 cups/day | 283 | 20 | 1.09 | 0.65–1.84 | 0.91 | 0.52–1.59 |
HbA1c (per 0.1% increase) | 1.36 | 1.30–1.42 | ||||
Women | ||||||
Age (years) | ||||||
46–55 (reference) | 1310 | 47 | 1 | 1 | ||
56–65 | 2907 | 139 | 1.18 | 0.83–1.67 | 0.76 | 0.52–1.11 |
66–75 | 1930 | 100 | 1.26 | 0.87–1.83 | 0.79 | 0.52–1.19 |
Body mass index‡ | ||||||
1st quartile (reference) | 1535 | 31 | 1 | 1 | ||
2nd quartile | 1538 | 59 | 1.92 | 1.23–2.99 | 1.86 | 1.18–2.96 |
3rd quartile | 1531 | 77 | 2.41 | 1.57–3.70 | 2.02 | 1.29–3.16 |
4th quartile | 1543 | 119 | 3.68 | 2.44–5.55 | 2.64 | 1.72–4.07 |
Smoking | ||||||
Never (reference) | 5953 | 279 | 1 | 1 | ||
Past | 59 | 3 | 1.17 | 0.35–3.83 | 1.92 | 0.56–6.57 |
Current (<20/day) | 96 | 3 | 0.92 | 0.28–2.96 | 0.76 | 0.21–2.70 |
Current (≥20/day) | 39 | 1 | 0.63 | 0.08–4.72 | 0.79 | 0.09–6.75 |
Alcohol intake | ||||||
Non‐drinker (reference) | 5447 | 262 | 1 | 1 | ||
1st tertile | 232 | 7 | 0.62 | 0.29–1.35 | 0.55 | 0.25–1.25 |
2nd tertile | 185 | 10 | 1.18 | 0.61–2.29 | 0.94 | 0.47–1.90 |
3rd tertile | 283 | 7 | 0.54 | 0.25–1.17 | 0.44 | 0.20–0.99 |
Family history of diabetes (+) | 768 | 69 | 2.47 | 1.85–3.30 | 1.69 | 1.23–2.32 |
Physical activity (leisure time) (active) | 1818 | 87 | 1.03 | 0.79–1.34 | 0.97 | 0.73–1.29 |
Walking | ||||||
<0.5 h/day (reference) | 768 | 39 | 1 | 1 | ||
0.5–0.9 h/day | 1342 | 62 | 0.89 | 0.58–1.36 | 0.89 | 0.57–1.40 |
1–1.9 h/day | 1368 | 66 | 0.94 | 0.61–1.44 | 0.84 | 0.53–1.33 |
≥2 h/day | 2669 | 119 | 0.94 | 0.63–1.41 | 0.80 | 0.52–1.22 |
Physical activity (daily) | ||||||
Light (reference) | 955 | 45 | 1 | 1 | ||
Moderate | 4466 | 209 | 1.02 | 0.72–1.46 | 0.99 | 0.68–1.44 |
Slightly heavy | 663 | 28 | 0.99 | 0.59–1.66 | 0.81 | 0.47–1.41 |
Heavy | 63 | 4 | 1.32 | 0.44–3.91 | 0.81 | 0.25–2.59 |
Hypertension (+) | 2392 | 148 | 1.42 | 1.11–1.83 | 1.52 | 1.16–1.99 |
Coffee intake | ||||||
<1 cups/day (reference) | 3967 | 196 | 1 | 1 | ||
1–1.9 cups/day | 1213 | 51 | 0.85 | 0.61–1.17 | 0.86 | 0.61–1.22 |
2–2.9 cups/day | 779 | 35 | 0.97 | 0.66–1.43 | 1.04 | 0.69–1.57 |
≥3 cups/day | 188 | 4 | 0.46 | 0.17–1.26 | 0.55 | 0.19–1.57 |
HbA1c (per 0.1% increase) | 1.52 | 1.45–1.59 |
*Adjusted for age, body mass index, smoking status, alcohol intake, family history of diabetes, leisure time physical activity, walking, daily physical activity, hypertension and coffee intake.
†Adjusted for variables listed above and baseline hemoglobin A1c (HbA1c) value.
‡Body mass index was divided into quartiles (1st quartile, <21.6 kg/m2 for men and <21.5 kg/m2 for women; 2nd quartile, 21.6–23.5 kg/m2 for men and 21.5–23.4 kg/m2 for women; 3rd quartile, 23.6–25.4 kg/m2 for men and 23.5–25.5 kg/m2 for women; 4th quartile, ≥25.5 kg/m2 for men and ≥25.6 kg/m2 for women).