TABLE 1.

Plasma parameters after trimetazidine treatment of HFD-induced obese mice

Plasma parameters in trimetazidine-treated HFD-induced obese mice. Ad libitum plasma was collected on day 22 after treatment, 2 hours into the dark cycle during animal euthanization, whereas fasted plasma was collected after a 6-hour fast on day 21 after treatment (n = 5–6). Values represent mean ± S.E.M.

	Ad Libitum Saline	6-h Fast Saline	Ad Libitum Trimetazidine	6-h Fast Trimetazidine
Glucose (mM)	7.95 ± 0.70	7.13 ± 0.29	7.83 ± 0.43	7.52 ± 0.56
Insulin (ng/ml)	4.41 ± 0.62	0.92 ± 0.11	4.21 ± 0.34	0.95 ± 0.08
TAG (mg/dl)	240.65 ± 12.52	254.89 ± 11.65	298.05 ± 16.24*	258.33 ± 12.26
FFA (mM)	0.38 ± 0.04	0.47 ± 0.04	0.33 ± 0.06	0.43 ± 0.03

FFA, free fatty acid.

^*P < 0.05, indicates a statistically significant difference from saline-treated counterpart.