Fig. 1.

Pudendal nerve stimulation inhibits bladder overactivity (i.e., smaller bladder capacity) caused by 0.25% AA irritation. (A) CMG traces during saline or AA infusion with or without PNS. The stimulation duration is indicated by the black bars under the bladder pressure traces. T, PNS threshold intensity for inducing anal sphincter twitch. T = 1 V. Infusion rate = 2 ml/min. (B) Bladder capacity measured during CMGs under different conditions (N = 5 cats). PNS, 5 Hz, 0.2 milliseconds. T = 0.3–1.8 V. *Significantly (P < 0.01) different from the AA control before PNS (one-way ANOVA).