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. 2014 Jun;349(3):402–407. doi: 10.1124/jpet.113.211557

Fig. 3.

Fig. 3.

Summarized results of dose-dependent effect of duloxetine on the following: (1) the capacity of the AA-irritated bladder and (2) PNS-induced increase in bladder capacity (N = 5 cats). Bladder capacity was normalized to saline control capacity before any treatment. PNS, 5 Hz, 0.2 milliseconds. T = 0.3–1.2 V. #Significantly (P < 0.05) different from AA control (two-way ANOVA). @Significantly (P < 0.05) different from the bladder capacity measured before duloxetine treatment (i.e., at 0 mg/kg of duloxetine); *significantly (P < 0.05) different from bladder capacity measured during PNS before duloxetine treatment (one-way ANOVA).