Fig. 5.
Summarized results showing that WAY100635 reverses the suppressive effect of duloxetine on pudendal inhibition of bladder overactivity caused by 0.25% AA irritation (N = 10 cats). Bladder capacity was normalized to saline control capacity before any treatment. PNS, 5 Hz, 0.2 milliseconds. T = 0.4–1.8 V. *Significantly (P < 0.05) different from the bladder capacity measured during PNS before any drug treatment (one-way ANOVA). #Significantly (P < 0.05) different from AA control (two-way ANOVA).