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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: NMR Biomed. 2013 Nov 28;27(2):163–174. doi: 10.1002/nbm.3048

Figure 4. Lorentzian vs. asymmetry analysis.

Figure 4

(a) Acute FLuid Attenuated Inversion Recovery (FLAIR) and (b) the segmented regions-of-interest overlaid on the acute FLAIR image in an example patient (Patient 4; Table 1), along with the hyperacute amide proton transfer (APT) maps calculated from the (c) Lorentzian method (d) and asymmetry method. A coronal slice and two axial slices are shown. APT effects are reduced on the acutely ischemic (right) side (white arrows), as well as in regions of prior infarct (purple arrows). The Lorentzian method provides contrast more visually consistent with the pathology than does the asymmetry method, which may be attributed to intra-scan motion across offsets and concomitant MT/NOE/aliphatic contamination of the APT effect. Both methods are compared in Fig. 6.