Table 2. Factors associated with overall mortality in patients who receive HAIC or symptomatic treatment.

	Univariate analysis			Multivariate analysis
	Hazard ratio	95% CI	P	Hazard ratio	95% CI	P
Age (>65 vs. <65 yrs)	1.175	0.774–1.785	0.449
Sex (Male vs. female)	1.113	0.655–1.890	0.692
Child’s classification (A vs. B)	0.430	0.279–0.662	<0.001	0.537	0.321–0.901	0.019
PV thrombosis (yes vs. no)	1.346	0.880–2.059	0.171
AFP level (>1000 vs <1000 ng/ml)	0.683	0.450–1.036	0.073
Okuda stage (I vs. II–III)	0.608	0.311–1.189	0.146
HAIC vs symptomatic treatment	0.394	0.258–0.603	<0.001	0.321	0.200–0.515	<0.001
CLIP sore (1–3 vs. 4–6)	0.482	0.315–0.736	0.001	0.611	0.375–0.997	0.048
BCLC stage (A–B vs. C–D)	0.562	0.348–0.908	0.018

HAIC: Hepatic arterial infusion chemotherapy, CLIP: Cancer of the Liver Italian Program, BCLC: Barcelona Clinic Liver Cancer.