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. 2014 May 13;9(5):e97350. doi: 10.1371/journal.pone.0097350

Figure 3. IL-22 inhibits CCL20 promoter reporter activities in AGS cells infected with H. pylori.

Figure 3

AGS cells were co-transfected with the CCL20 luciferase reporter construct pGL3-862 or pGL3-3491 along with pRL-TK Renilla luciferase plasmid. At 48 h after transfection, cells were infected with H. pylori in the presence or absence of IL-22. Luciferase activities were normalized to the expression of the cotransfected pRL-TK Renilla luciferase plasmid. The activity from each construct is presented as the relative luciferase activity of H. pylori-infected cells versus uninfected cells (open bar; set as 1). Data represent the mean ± SEM from three independent experiments. *, p<0.05; **, p<0.01 for H. pylori + IL-22 versus H. pylori only.