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. Author manuscript; available in PMC: 2015 May 25.
Published in final edited form as: Chem Biol Interact. 2014 Mar 13;215:33–39. doi: 10.1016/j.cbi.2014.02.015

Table 2.

Effects of one concentration, 38 mM, of several anions in modulating DCA-induced GSTZ1 inactivation in a single human liver cytosol

Anion added % activity lost
None 92%
Fluoride 87%
Chloride 20%
Bromide 7%
Iodide 2%
Sulfite 10%
Sulfate 85%
Carbonate 91%
Cyanide 97%
Acetate 98%

The human liver cytosol used was an EGT/EGT sample; sodium or potassium salts at a concentration of 38 mM were used in duplicate 2 h incubations with 0.5 mM DCA. The reference cytosol sample was incubated for 2 h without DCA and its activity was used to calculate % activity lost.