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. 2014 May 7;9:2167–2178. doi: 10.2147/IJN.S60178

Table 2.

IC50 of F-L-imatinib, L-imatinib, and free imatinib against HeLa cells and A549 cells at 72 hours

Treatment group IC50 (μM) of HeLa IC50 (μM) of A549
F-L-imatinib 151±15.5 >1,200
L-imatinib 906±67.1* >1,200
Free imatinib 15.7±1.3* 34.6±3.6

Notes: Each value represents the mean ± SD (n=5);

*

P<0.05, versus F-L-imatinib.

Abbreviations: F-L-imatinib, folate receptor-targeted liposomal imatinib; IC50, half maximal inhibitory concentration; L-imatinib, non-targeted liposomal imatinib; SD, standard deviation.