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. 2014 May 7;7:117–127. doi: 10.2147/IDR.S39639

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© 2014 McNeil. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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A schematic depiction of selected Staphylococcus aureus mechanisms for immune evasion.

Notes: Cna interacts with C1q preventing formation of the C1qrs complex. ClfA and SdrE each promote Factor I mediated conversion of C3b to iC3b. Protein A is depicted binding to the Fc region of IgG preventing immunoglobulin opsonization.

Abbreviations: ClfA, staphylococcal clumping factor A; Cna, collagen adhesin; IgG, immunoglobulin G; PVL, Panton–valentine leukocidin; SdrE, S. aureus surface protein.