Table 3.
IOP | Screening | Baseline washout | Month 1 | Month 3 | Month 6 | Month 9 | Month 12 |
---|---|---|---|---|---|---|---|
Two iStent inject (N=94) | |||||||
IOP over time | |||||||
N | 94 | 94 | 93 | 94 | 93 | 94 | 94 |
Mean (SD) | 21.1 (1.7) | 25.2 (1.4) | 13.3 (4.1) | 12.8 (3.2) | 12.7 (3.2) | 12.9 (2.9) | 13.0 (2.3) |
IOP change from screening | |||||||
N | 93 | 94 | 93 | 94 | 94 | ||
Mean (SD) | −7.7 (4.2) | −8.3 (3.3) | −8.5 (2.8) | −8.2 (3.0) | −8.1 (2.6) | ||
IOP change from baseline | |||||||
N | 93 | 94 | 93 | 94 | 94 | ||
Mean (SD) | −11.8 (4.2) | −12.4 (3.4) | −12.5 (3.2) | −12.3 (3.0) | −12.2 (2.5) | ||
Two medications (N=98) | |||||||
IOP over time | |||||||
N | 98 | 98 | 96 | 95 | 91 | 92 | 90 |
Mean (SD) | 20.7 (1.7) | 24.8 (1.7) | 12.8 (2.6) | 12.5 (2.8) | 12.2 (2.2) | 12.8 (2.9) | 13.2 (2.0) |
IOP change from screening | |||||||
N | 96 | 95 | 91 | 92 | 90 | ||
Mean (SD) | −7.9 (2.9) | −8.1 (2.6) | −8.3 (2.4) | −7.7 (2.8) | −7.3 (2.2) | ||
IOP change from baseline | |||||||
N | 96 | 95 | 91 | 92 | 90 | ||
Mean (SD) | −12.0 (2.9) | −12.3 (2.8) | −12.6 (2.4) | −11.9 (2.8) | −11.6 (2.2) |
Abbreviations: IOP, intraocular pressure; SD, standard deviation.