Figure 2.
Structural characterization of the aggregates, by fluorescence and dynamic light scattering.
Notes: (A) Fluorescence intensity of the ANS fluorophore at 480 nm as a function of PAs concentration: (C18)2-L-gB498–505 (□), (C18)2-L-gD301–309 (▲), and (C18)2-L-gB498–505/(C18)2-L-gD301–309 (•). CMC values were established from the graphical break point; (B) DLS spectra of (C18)2-L-gB498–505/(C18)2-L-gD301–309 mixed aggregates at 25°C and 1 × 10−4 M concentration.
Abbreviations: ANS, 8-anilino-1-naphthalene sulfonic acid ammonium salt; CMC, critical micelle concentration; DLS, dynamic light scattering; PA, peptide amphiphile.