Table 2. Comparison of miRNA Families in B. malayi and C. elegans.
nematode | total miRNAs | total hairpins | afamilies of paralogues | bsingleton families | ctotal families | dshared families | eunique families |
B.malayi | 145 | 129 | 20 | 79 | 99 | 48 | 51 |
C.elegans | 195 | 175 | 40 | 61 | 101 | 48 | 53 |
MicroRNAs sharing a minimum of 6 contiguous nt between positions 1–7 at the 5′ end or that exhibit ≥70% identity overall in the absence of a conserved 5′ end were grouped into families of paralogues. In B. malayi, 66 miRNAs were grouped into 20 families (Table S5). In C. elegans, 134 miRNAs were grouped into 40 families (Table S6).
The remaining miRNAs in each nematode that do not fall within a paralogous group are considered individual families consisting of a single member.
Total number of families = number of paralogous families + number of singleton families.
48 miRNA families are shared between B. malayi (75 miRNAs) and C. elegans (113 miRNAs). See Table S7 for details.
Number of families in a nematode with a seed sequence that is not found in the other nematode.