Table 2. Measles case fatality rate by selected variables, in 16 outbreaks, Bihar, India, October 2011 to April 2012.
Variable | Measlescases (%) | Measlesassociated death | Adjusted CFR(%) (95% CI) | Odds Ratio(95% CI) | P |
All | 3670 | 28 | 0.78 (0.47–1.30) | ||
Age (years) | |||||
> = 5 | 2034 (55.4) | 8 | 0.42 (0.26–0.67) | 1 | |
1–4 | 1423 (38.8) | 15 | 1.06 (0.52–2.17) | 2.57 (1.27–5.18) | 0.001 |
<1 | 213 (5.8) | 5 | 2.29 (1.04–4.95) | 5.60 (2.27–13.79) | 0.012 |
<5 | 1636 (44.6) | 20 | 1.22 (0.66–2.27) | ||
Sex | |||||
Male | 1876 (51.1) | 12 | 0.67 (0.36–1.24) | 1 | |
Female | 1794 (48.9) | 16 | 0.90 (0.54–1.49) | 1.36 (0.84–2.19) | 0.196 |
Religion | |||||
Others | 1179 (32.1) | 6 | 0.50 (0.30–0.83) | 1 | |
Hindu | 2491 (67.9) | 22 | 0.91 (0.48–1.71) | 1.83 (0.93–3.59) | 0.076 |
Caste | |||||
General/OBC | 2679 (73.0) | 11 | 0.42 (0.20–0.88) | 1 | |
Scheduled caste/Tribe | 991 (27.0) | 17 | 1.72 (1.05–2.81) | 4.12 (2.37–7.19) | 0.000 |
Education of head of the household | |||||
Primary and above | 1190 (32.4) | 2 | 0.21 (0.06–0.68) | 1 | |
Illiterate | 2480 (67.6) | 26 | 1.06 (0.60–1.88) | 5.23 (1.21–22.61) | 0.029 |
Family income | |||||
Above poverty line | 893 (24.3) | 3 | 0.38 (0.12–1.17) | 1 | |
Below poverty line | 2777 (75.7) | 25 | 0.91 (0.60–1.37) | 2.41 (1.10–5.72) | 0.030 |
Measles vaccination status | |||||
Vaccinated | 988 (26.9) | 7 | 0.83 (0.36–1.90) | 1 | |
Not vaccinated/Unknown* | 2682 (73.1) | 21 | 0.77 (0.48–1.21) | 0.92 (0.50–1.71) | 0.783 |
Vit A given during illness | |||||
Yes | 1288 (35.1) | 2 | 0.12 (0.06–0.27) | 1 | |
No/unknown** | 2382 (64.9) | 26 | 1.15(0.65–2.03) | 9.31 (3.88–22.35) | 0.000 |
Treatment during the illness | |||||
Public/private health facility | 437 (11.9) | 3 | 0.55 (0.09–3.28) | 1 | |
Bought from pharmacy | 277 (7.5) | 1 | 0.19 (0.02–2.29) | 0.35 (0.03–4.61) | 0.397 |
From Traditional healer/No treatment | 2956(80.5) | 24 | 0.87 (0.44–1.71) | 1.58 (0.15–16.64) | 0.683 |
Treatment at the public health facility | |||||
Yes | 115 (3.1) | 0 | 0 | ||
No | 3555 (96.9) | 28 | 0.81 (0.48–1.37) | ||
Median interval in days between onset of first case and notification of outbreak | |||||
<49 days (8 outbreaks) | 916 (25.0) | 3 | 0.28 (0.10–0. 79) | 1 | 0.038 |
> = 49 days (8 outbreaks) | 2754 (75.0) | 25 | 0.91 (0.63–1.31) | 3.25 (1.08–9.78) | |
Median interval between the notification and outbreak response | 0.093 | ||||
<17 days (7 outbreaks) | 2698 (73.5) | 24 | 0.89 (0.58–1.34) | 1 | |
> = 17 days (9 outbreaks) | 972 (26.5) | 4 | 0.42 (0.19–0.92) | 0.47 (0.19–1.15) | |
Median interval between the onset and outbreak response | 0.280 | ||||
<70 days (8 outbreaks) | 802 (21.9) | 4 | 0.42 (0.11–1.52) | 1 | |
> = 70 days) (8 outbreaks) | 2868 (78.1) | 24 | 0.86 (0.56–1.32) | 2.05 (0.52–8.08) | |
Median number of cases per outbreak | |||||
<114 cases (7 outbreaks) | 717 (19.5) | 4 | 0.52 (0.19–1.45) | 1 | |
> = 114 cases (9 outbreaks) | 2953 (80.5) | 24 | 0.84 (0.52–1.35) | 1.62 (0.52–5.07) | 0.378 |
Order of case within the household | |||||
>1 case in household, not first case | 1821 (49.6) | 11 | 0.66 (0.37–1.19) | 1 | |
>1 case in household, first case | 1008 (27.5) | 11 | 1.05 (0.68–1.62) | 1.59 (0.86–2.96) | 0.132 |
Single case | 841 (22.9) | 6 | 0.71 (0.25–1.98) | 1.07 (0.54–2.14) | 0.832 |
Order of cases within household | |||||
>1 case in household, not 1st case | 1821 (49.6) | 11 | 0.66 (0.37–1.19) | 1 | |
>1 case in household,1st case/single case in household | 1849 (50.4) | 17 | 0.90 (0.52–1.54) | 1.35 (0.87–2.10) | 0.161 |
*MCV1 status of 455 (12.4%) of children was unknown, **Vitamin A administration status of 179 (4.9%) children was unknown.