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. 2014 May 13;9(5):e96668. doi: 10.1371/journal.pone.0096668

Table 2. Measles case fatality rate by selected variables, in 16 outbreaks, Bihar, India, October 2011 to April 2012.

Variable Measlescases (%) Measlesassociated death Adjusted CFR(%) (95% CI) Odds Ratio(95% CI) P
All 3670 28 0.78 (0.47–1.30)
Age (years)
> = 5 2034 (55.4) 8 0.42 (0.26–0.67) 1
1–4 1423 (38.8) 15 1.06 (0.52–2.17) 2.57 (1.27–5.18) 0.001
<1 213 (5.8) 5 2.29 (1.04–4.95) 5.60 (2.27–13.79) 0.012
<5 1636 (44.6) 20 1.22 (0.66–2.27)
Sex
Male 1876 (51.1) 12 0.67 (0.36–1.24) 1
Female 1794 (48.9) 16 0.90 (0.54–1.49) 1.36 (0.84–2.19) 0.196
Religion
Others 1179 (32.1) 6 0.50 (0.30–0.83) 1
Hindu 2491 (67.9) 22 0.91 (0.48–1.71) 1.83 (0.93–3.59) 0.076
Caste
General/OBC 2679 (73.0) 11 0.42 (0.20–0.88) 1
Scheduled caste/Tribe 991 (27.0) 17 1.72 (1.05–2.81) 4.12 (2.37–7.19) 0.000
Education of head of the household
Primary and above 1190 (32.4) 2 0.21 (0.06–0.68) 1
Illiterate 2480 (67.6) 26 1.06 (0.60–1.88) 5.23 (1.21–22.61) 0.029
Family income
Above poverty line 893 (24.3) 3 0.38 (0.12–1.17) 1
Below poverty line 2777 (75.7) 25 0.91 (0.60–1.37) 2.41 (1.10–5.72) 0.030
Measles vaccination status
Vaccinated 988 (26.9) 7 0.83 (0.36–1.90) 1
Not vaccinated/Unknown* 2682 (73.1) 21 0.77 (0.48–1.21) 0.92 (0.50–1.71) 0.783
Vit A given during illness
Yes 1288 (35.1) 2 0.12 (0.06–0.27) 1
No/unknown** 2382 (64.9) 26 1.15(0.65–2.03) 9.31 (3.88–22.35) 0.000
Treatment during the illness
Public/private health facility 437 (11.9) 3 0.55 (0.09–3.28) 1
Bought from pharmacy 277 (7.5) 1 0.19 (0.02–2.29) 0.35 (0.03–4.61) 0.397
From Traditional healer/No treatment 2956(80.5) 24 0.87 (0.44–1.71) 1.58 (0.15–16.64) 0.683
Treatment at the public health facility
Yes 115 (3.1) 0 0
No 3555 (96.9) 28 0.81 (0.48–1.37)
Median interval in days between onset of first case and notification of outbreak
<49 days (8 outbreaks) 916 (25.0) 3 0.28 (0.10–0. 79) 1 0.038
> = 49 days (8 outbreaks) 2754 (75.0) 25 0.91 (0.63–1.31) 3.25 (1.08–9.78)
Median interval between the notification and outbreak response 0.093
<17 days (7 outbreaks) 2698 (73.5) 24 0.89 (0.58–1.34) 1
> = 17 days (9 outbreaks) 972 (26.5) 4 0.42 (0.19–0.92) 0.47 (0.19–1.15)
Median interval between the onset and outbreak response 0.280
<70 days (8 outbreaks) 802 (21.9) 4 0.42 (0.11–1.52) 1
> = 70 days) (8 outbreaks) 2868 (78.1) 24 0.86 (0.56–1.32) 2.05 (0.52–8.08)
Median number of cases per outbreak
<114 cases (7 outbreaks) 717 (19.5) 4 0.52 (0.19–1.45) 1
> = 114 cases (9 outbreaks) 2953 (80.5) 24 0.84 (0.52–1.35) 1.62 (0.52–5.07) 0.378
Order of case within the household
>1 case in household, not first case 1821 (49.6) 11 0.66 (0.37–1.19) 1
>1 case in household, first case 1008 (27.5) 11 1.05 (0.68–1.62) 1.59 (0.86–2.96) 0.132
Single case 841 (22.9) 6 0.71 (0.25–1.98) 1.07 (0.54–2.14) 0.832
Order of cases within household
>1 case in household, not 1st case 1821 (49.6) 11 0.66 (0.37–1.19) 1
>1 case in household,1st case/single case in household 1849 (50.4) 17 0.90 (0.52–1.54) 1.35 (0.87–2.10) 0.161

*MCV1 status of 455 (12.4%) of children was unknown, **Vitamin A administration status of 179 (4.9%) children was unknown.