Table 2.
Summary of Medication Adherence and Tolerability for TAU+SCT participants
| Self-report | Pill/Cartridge Count |
|
|---|---|---|
| Medication Adherence | ||
| Percentage of bupropion taken, mean (std. dev.) | 92.4%a(15.6%) | 94.5%b(14.9%) |
| Average nicotine inhaler cartridges used per day (over all active treatment weeks): | ||
| < 1 Cartridge, n (%) | 139 (56.3)c | 148 (62.2)d |
| ≥ 1 but < 4 Cartridges, n (%) | 69 (27.9)c | 63 (26.5)d |
| ≥ 4 but < 6 Cartridges, n (%) | 21 (8.5)c | 14 (5.9)d |
| ≥ 6 Cartridges (as prescribed), n (%) | 18 (7.3)c | 13 (5.5)d |
| Medication Tolerability | ||
| Tolerability of maximum bupropion dose: | ||
| Reached maximum, n (%) | 258 (97.7) | NA |
| Sustained dose at maximum, n (%) | 190 (72.0) | NA |
Self-reported adherence was calculated by dividing the number of milligrams reported taken by the number of milligrams prescribed, and multiplying by 100;
pill count adherence was calculated by taking the number of pills dispensed minus the number returned or reported lost divided by the number of pills prescribed to be taken and multiplying by 100.
Self-reported adherence was calculated by dividing the number of cartridges reported taken by the number of days assessed, and multiplying by 100;
cartridge count adherence was calculated by dividing the number of used cartridges returned by the number of days assessed and multiplying by 100. In cases where participants failed to return their medication bottles/cartridges, those bottles/ cartridges were excluded from the analysis.