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. Author manuscript; available in PMC: 2015 Apr 20.
Published in final edited form as: Adv Drug Deliv Rev. 2013 Dec 17;0:67–80. doi: 10.1016/j.addr.2013.12.002

Table 1.

Comparison of different tissue engineered kidney disease models

Disease Cell Source Reference
Polycystic Kidney Disease MDCK [44,84-87,89,91-93]
Mouse
   Immortalized
   collecting duct		 [94]
   PKD1null/null
   embryonic kidney
   with fibroblasts		 [13,98]
   Inner Medullary
   Collecting Duct cells		 [58]
Human primary epithelial cells
from ADPKD cysts		 [91,96,97,99-101,103]
Drug-Induced Nephrotoxicity MDCK [45,46]
Mouse Kidney Tubule [50,51]
Human
   Immortalized
   proximal tubule
   epithelial cells		 [6]
   Primary proximal
   tubule epithelial cells		 [34]
Fibrosis Human proximal tubule
epithelial cells with dermal
fibroblasts		 [48]
Renal Cell Carcinoma Human RCC cells [12,127-129]
Nephronophthisis Mouse Inner Medullary
Collecting Ducts cells		 [130]