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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Bioorg Med Chem Lett. 2014 Mar 20;24(9):2193–2197. doi: 10.1016/j.bmcl.2014.03.016

Table 1.

IC50 values for diadamantyl urea-based sEH inhibitors 1a–f*.

graphic file with name nihms577781u1.jpg
Z n # IC50 (nM)a
-(CH2)n- 2 1a 179.2
4 1b 26.3
6 1c 0.4
8 1d 7.3
graphic file with name nihms577781t1.jpg 1e 779.6
graphic file with name nihms577781t2.jpg 1f 39.7
a

As determined via a kinetic fluorescent assay.25