Fig. 1.
Effects of antipsychotics on hyperlocomotion induced by MK-801. Each symbol represents mean ± SEM distance traveled (n = 7–8) in the 16–45-min period after MK-801 administration. Test compound or vehicle was administered 45 min before MK-801 (0.3 mg/kg). *p < 0.05, **p < 0.01, compared with MK-801-injected control group using Newman–Keuls post hoc test, following significant ANOVA. The lower dotted lines represent the average locomotor activity of vehicle/saline groups