Table 2.

Statistical summary of behavioral effects of drugs

Drug	MK-801 effect of MK-801 vs. saline	MK-801: effect of antipsychotics vs. vehicle	Spontaneous locomotor activity	Forced swim test	Step-through latency training session	Step-through latency test session
Chloropromazine	t(14) = 3.2, p < 0.01	F(3, 28) = 5.9, p < 0.01	F(3, 28) = 12.66, p < 0.01	F(3, 28) = 1.8, p > 0.05	H(3) = 8.96, p < 0.05	H(3) = 12.6, p < 0.01
Haloperidol	t(14) = 2.6, p < 0.05	F(3, 28) = 13.7, p < 0.01	F(3, 28) = 31.80, p < 0.01	F(4, 35) = 7.2, p < 0.01	H(3) = 18.2, p < 0.01	H(3) = 17.7, p < 0.01
Clozapine	t(14) = 4.0, p < 0.01	F(3, 28) = 13.8, p < 0.01	F(3, 28) = 5.50, p < 0.01	F(5, 42) = 4.2, p < 0.01	H(3) = 1.3, p > 0.05	H(3) = 10.7, p < 0.05
Olanzapine	t(14) = 4.2, p < 0.01	F(3, 28) = 3.6, p < 0.05	F(3, 28) = 6.10, p < 0.01	F(3, 28) = 5.2, p < 0.01	H(3) = 5.7, p > 0.05	H(3) = 7.1, p > 0.05
Risperidone	t(14) = 6.3, p < 0.01	F(4, 35) = 5.1, p < 0.01	F(3, 26) = 7.50, p < 0.01	F(4, 35) = 3.1, p < 0.05	H(3) = 11.5, p < 0.05	H(3) = 11.2, p < 0.05
Aripiprazole	t(14) = 4.8, p < 0.01	F(4, 35) = 0.5, p > 0.05	F(4, 39) = 12.10, p < 0.01	F(4, 34) = 2.9, p < 0.05	H(3) = 9.6, p < 0.05	H(3) = 3.0, p > 0.05
Lurasidone	t(14) = 3.2, p < 0.01	F(3, 28) = 7.7, p < 0.01	F(3, 28) = 10.8, p < 0.01	F(3, 28) = 6.5, p < 0.01	(3) = 3.0, p > 0.05	H(3) = 10.0, p < 0.05
Asenapine	t(14) = 4.6, p < 0.01	F(3, 28) = 5.6, p < 0.01	F(3, 28) = 8.1, p < 0.01	F(3, 28) = 6.5, p < 0.01	H(3) = 9.3, p < 0.05	H(3) = 13.3, p < 0.05
Imipramine	n.t.	n.t.	n.t.	F(2, 21) = 5.1, p < 0.05	n.t.	n.t.
Scopolamine	n.t.	n.t.	n.t.	n.t.	H(3) = 2.7, p > 0.05	H(3) = 16.5, p < 0.01

n.t. not tested